ABSTRACT
Disposition of (-)-norepinephrine and (-)-epinephrine in jejunum of WLH chicken was studied using oil-immersion technique. The relative rate of different routes of disposition of catecholamines was in the following order: for (-)-NE COMT greater than or equal to MAO greater than or equal to U2 greater than U1, for (-)-Epi U2 greater than or equal to COMT greater than MAO greater than U1. The role of enzymatic degradation is almost equal to that of uptake processes for (-)-Epi, but it was greater for (-)-NE.
Subject(s)
Animals , Catechol O-Methyltransferase/physiology , Chickens , Epinephrine/pharmacokinetics , Female , Jejunum/metabolism , Male , Neurons/metabolism , Norepinephrine/pharmacokineticsSubject(s)
Animals , Chickens , Crop, Avian/drug effects , Esophagus/drug effects , Female , Histamine/toxicity , Male , Promethazine/toxicity , Proventriculus/drug effectsSubject(s)
Animals , Chickens , Epinephrine/metabolism , Female , Male , Norepinephrine/metabolism , Spleen/metabolismSubject(s)
Animals , DDT/pharmacology , Malathion/pharmacology , Male , Mice , Sleep/drug effects , Thiopental/pharmacologyABSTRACT
5-Hydroxytryptamine and histamine were estimated in lungs, liver, spleen and adrenals of chicken. A substantial amount of both the amines was found in all the organs. The highest level of both the amines was found in adrenals followed by spleen, lungs and liver. The level of 5-hydroxytryptamine was, however, higher than histamine in all the tissues except adrenals.